Guide to Vaccine Contraindications and Precautions . Contraindicated in patients hypersensitive to oxycodone or acetaminophen. Acetaminophen is an analgesic used to temporarily relieve minor aches and pains due to headache, muscular aches, backache, minor pain of arthritis, the common cold, toothache, and premenstrual and menstrual cramps.Acetaminophen is also used to temporarily reduce fever. Bottles of 100 NDC 63481-627-70. It works by changing the way the body senses pain and by cooling the body. Jessica Ellis Date: March 31, 2022 An allergy to aspirin is a common contraindication for an NSAID.. Non-steroidal anti-inflammatory drugs have several contraindications that may limit or prohibit use.While many people can use NSAIDs safely and effectively for pain reduction and other conditions, certain health conditions can make the use of these drugs inadvisable and even dangerous. It works by changing the way the body senses pain and by cooling the body. The content of 194.19. Acetaminophen may also be used to relieve the pain of osteoarthritis (arthritis caused by the breakdown of the lining of the joints). Using data from this study, an infant would receive a maximum . Some of the more common ones include Nardil, Parnate and . Learn its side effects, dosages, and risk of addiction and dependence. The purpose of this article was to review the pharmacodynamics, indications, contraindications, and precautions for the use of intravenous acetaminophen in pediatrics. The usual adult dosage is one tablet every 6 hours as needed for pain. Acetaminophen is in a class of medications called analgesics (pain relievers) and antipyretics (fever reducers). <50 kg: 12.5 mg/kg IV q4hr OR 15 mg/kg IV q6hr; not to exceed 750 mg/dose or 3.75 g/day. CONTRAINDICATIONS METANX® is contraindicated in patients with known hypersensitivity to any of the components contained in this product. Consider giving acetaminophen before DTaP and every 4 hours thereafter for 24 hours Persons with moderate or severe illnesses, with or without fever, can be vaccinated as soon as : N OTES: Note 1: If you have an emergency or a serious medical question, please contact a medical professional or call 911 immediately. Finasteride Contraindications. Taking large amounts of Tylenol can harm your liver. Acetaminophen is a commonly used pediatric medication that has recently been approved for intravenous use in the United States. Pain relief, fever reducer. . Medications and Health Conditions that Pose Considerable Risk to MDMA Users Known Contraindicated Medications: Monoamine Oxidase Inhibitors (MAO Inhibitors, or MAOIs) A MAO Inhibitor ("MAO" is pronounced like "cow") is a type of prescription antidepressant. The most common side effects of Tylenol include: nausea, stomach pain, Risk of Medication Errors 5.4 Allergy and . What is acetaminophen? However, there is a general debate among experts whether hepatic impairment is truly a limiting factor, as it would likely be associated with decreased production of the toxic metabolite, N-acetyl . Precautions and Contraindications Generally speaking, acetaminophen is a safe medication, but there are precautions to keep in mind before taking it or giving it to a child: Don't take acetaminophen if you have a history of liver disease. Tylenol (acetaminophen) is an analgesic (pain reliever) and antipyretic (fever reducer) to relieve fever as well as aches and pains associated with many conditions. More than 500 OTC and prescription medicines contain acetaminophen. We will learn the drug classification, contraindications, and interactions. Covid vaccines come with some side effects, which is a sign that your . Serious reactions are fairly rare, but symptoms can include itching, rashes, dizziness, difficulty in breathing, or swelling. 5 mg/325 mg. Blue, round, tablet, debossed with "PERCOCET" and "5" on one side and bisect on the other. Contraindications to the use of acetaminophen include hypersensitivity to acetaminophen, severe hepatic impairment, or severe active hepatic disease. It is used to treat many conditions such as headache, muscle aches, arthritis, backache, toothaches, colds, and fevers. acetaminophen 325 mg, 1 tablet every 6 hrs. Click to view Tylenol detailed prescribing information. Patients who take anticoagulants or antiplatelet medications, 2,3 corticosteroids, certain antihypertensive agents, 4 or aspirin may face increased risks when also taking certain OTC pain relievers. Paracetamol is intended to be used only as recommended on the medication label or as directed by a medical doctor. Infuse IV over at least 15 minutes . Before you have any medical tests, tell the person in charge if you have taken acetaminophen within the past 3 or 4 days. Methotrexate Contraindications and Risk Factors for Serious Adverse Events in Inflammatory Disorders Recommendations for Use February 2020 VA Pharmacy Benefits Management Services, Medical Advisory Panel, and VISN Pharmacist Executives The following recommendations are based on medical evidence, clinician input, and expert opinion. In this lesson, we will learn more about lidocaine. Among other contraindications of ibuprofen, over-consumption of more than 2400mg daily is associated with the occurrence of arterial thrombosis. Fioricet is intended as a treatment for tension headache. Propranolol Contraindications. 4 CONTRAINDICATIONS 5 WARNINGS AND PRECAUTIONS 5.1 Concurrent Active Severe Infections 5.2 Vaccinations 5.3 Infusion Related Reactions and Hypersensitivity 5.4 Gastrointestinal Perforation 6 ADVERSE REACTIONS 6.1 Clinical Trials Experience 7 DRUG INTERACTIONS (If underlying neurologic disorder is involved, also see fiNeurologic disorders.fi) Note 4: Not a contraindication, but a precaution. 10 It is also used for its antipyretic effects, helping to reduce fever. Carefully check the labels of all other medicines you are using, because they may also contain acetaminophen. ACETAMINOPHEN INJECTION safely and effectively. . Pink, oval, tablet debossed with "PERCOCET" on one side and "2.5" on the other. Tylenol extra strength (i.e. . Acetaminophen may also be used to relieve the pain of osteoarthritis (arthritis caused by the breakdown of the lining of the joints). 2. There is a danger that this successful immunization program may lead to complacency about vaccine preventable illnesses such that parents, and sometimes physicians . You may also call the laboratory ahead of time to find out whether acetaminophen will cause a problem. Acetaminophen was undetectable (<0.5 mg/L) in all mothers 12 hours after the dose. Drug Name Generic Name: acetaminophen (N-acetyl-p-aminophenol) Brand Name: Suppositories: Abenol (CAN), Acephen Oral: Aceta, Apacet, Atasol (CAN), Genapap, Genebs, Liquiprin, Mapap, Panadol, Tapanol, Tempra,Tylenol Classification: Antipyretic, Analgesic (nonopioid) Pregnancy Category B Dosages ADULTS PO or PR By suppository, 325-650 mg q 4-6 hr or PO, 1,000 mg tid to qid. Taking quantities of paracetamol that are higher than is recommended (or directed by a medical doctor) is not advisable. Drug: caffeine, benadryl, codeine, fluticasone nasal, hydrocodone, ibuprofen, guaifenesin, predisone, tramadol, naproxen. There are certain groups that should never use Tylenol #3. C 8 H 10 N 4 O 2 Mol. Taking more than one medicine containing acetaminophen at a time can increase the chance of taking too much (more than 4,000 mg in 24 hours), which can lead to severe liver damage.. Contraindications for activated charcoal use. Tylenol #3 is a prescription painkiller that combines acetaminophen with codeine. 500 mg/tablet or capsule): It is not to exceed 3 g/day; under the supervision of healthcare professionals such as doctors, daily doses of up to 4 g/day may be used. Uses It is an 'over counter drugs' , there are the following uses Acetaminophen may interfere with the results of some medical tests. Acetaminophen CM Pain reliever. 23 This drug was initially approved by the U.S. FDA in 1951 and . Hypersensitivity to acetaminophen or phenacetin; use with alcohol. OTHER ACETAMINOPHEN-CONTAINING MEDICINES. Contraindications and Precautions 1. The different abuterol contraindications relate to patients who have previously shown a hypersensitivity to the drug or any of its components, and those with heart arrhythmias. Get medical help right away, if you have any of the symptoms listed above. The available dosages are oxycodone/acetaminophen 2.5/325, 7 . Do not exceed 4 g . Generally as substitute for aspirin when the latter is not tolerated or is contraindicated. Liver warning: This product contains acetaminophen. Note 3: Consider giving acetaminophen before DTP or DTaP and every 4 hours thereafter for 24 hours to children who have a personal or a family history of convulsions. acetaminophen ; Contraindications ; acetaminophen Common Brand(s): Panadol, Tylenol . Acetaminophen is available under the following different brand names: Tylenol, Tylenol Arthritis Pain, Tylenol Ext, Little . Don't take more than three grams (about six extra-strength pills, or nine regular pills) in a day. Acetaminophen / poisoning Adsorption Animals . Fever reduction. PERCOCET (Oxycodone and Acetaminophen Tablets, USP) is supplied as follows: 2.5 mg/325 mg. taking over the recommended maximum dosage amount of 1000mg of acetaminophen . 2. Nonallergic bronchospasms such as chronic bronchitis or emphysema. Contraindications for activated charcoal use Ann Emerg Med. Pain & Fever. Contraindications for MMR vaccination include history of a severe (anaphylactic) reaction to a previous dose or to any component of the vaccine (such as gelatin or neomycin), pregnancy and immunosuppression. Mechanism : The analgesic and antipyretic effects of paracetamol are believed to be related to the inhibition of prostaglandin synthetase (a mechanism shared by ASA and related drugs). Consider carefully the benefits and risks . 1980 Nov;9(11):599. doi: 10.1016/s0196-0644(80)80241-1. Dengue- ONLY use in persons who have laboratory confirmation of previous dengue infection AND reside in endemic dengue areas (b) ( 38) Severe allergic reaction (e.g., anaphylaxis) after a previous dose or to a vaccine component. Contraindications for activated charcoal use. Acetaminophen has been associated with cases of acute liver failure, at times resulting in liver transplant and death. Caution use in patients with anemia or cardiac, pulmonary, renal, or hepatic disease Nursing Implications 1. It inhibits prostaglandin synthesis in the CNS. ----- CONTRAINDICATIONS -----­ Acetaminophen is contraindicated: In patients with known hypersensitivity to acetaminophen or to . Allergic reactions are one the contraindications for acetaminophen use. Cautious Use Tylenol relieves pain in mild arthritis but has no effect on the underlying inflammation, redness, and swelling of the joint. The infant and childhood immunization program in Canada has led to extraordinary decreases in serious infections with diphtheria, tetanus, pertussis, polio, Haemophilus influenzae type b, hepatitis B, measles, mumps and rubella. CONTRAINDICATIONS NSAID or Ibuprofen use within previous 6 hours PRECAUTIONS Allergy or sensitivity to ASA or NSAIDS Patient on anticoagulation therapy Current active bleeding History of peptic ulcer disease or GI bleed Pregnant If asthmatic, no prior use of ASA or other NSAIDs CVA or TBI in the previous 24 hours Authors J E Jackson, . Acetaminophen warnings and acetaminophen side effects for adults. WebMD provides common contraindications for Acetaminophen W/Codeine oral. Temporary relief of mild to moderate pain. The study examined data from more than 5,400 older adults living in nursing . Ibuprofen is a common, over-the-counter medication used to treat pain and inflammation. In addition, acetaminophen lowers body temperature in individuals with a fever. Age >2 months (5 kg): 80 mg per dose. Ext release 1300 mg orally every 8 hrs. Patients with a hypersensitivity to the drug may experience bronchospasms, rash, and hives. Acetaminophen is frequently given by physicians to lessen fever and irritability associated with DTP vaccination, and it may be useful in preventing seizures among febrile-convulsion-prone children. Headache: Because headache often involves a significant psychological component, an opioid analgesic should only be employed for the treatment of headache when no other treatment is Tylenol may cause serious side effects including: rash, itching or swelling (especially of the face, tongue or throat), severe dizziness, and. The total daily dose of acetaminophen should not exceed 4 grams. Severe liver damage may occur if you take more than 4,000 mg of acetaminophen in 24 hours, with other drugs containing acetaminophen, and/or 3 or more alcoholic drinks every day while using this product. Acetaminophen is intended for temporary use only - should not be given for more than 4 - 5 days without physician reassessment. Inactive Ingredients: crospovidone, FD&C Blue #1 (aluminum lake), magnesium stearate, microcrystalline cellulose, povidone, pregelatinized starch, and stearic acid. Dehydration risk: 10 mg/kg every 6 hours. Adult & childn >12 yr 1-2 tab every 4-6 hr while symptoms last. PDR Drug Summaries are concise point-of-care prescribing, dosing and administering information to help phsyicans more efficiently and accurately prescribe in their practice PDR's drug summaries are available free of charge and serve as a great resource for US based MDs, DOs, NPs and PAs in patient practice PRECAUTIONS, CONTRAINDICATIONS, and. Authors J E Jackson, . Precautions to MMR administration include acute severe illness, high-dose steroid use, recent receipt of a blood product or a history . Oral: immediate release 325 mg to 1 g orally every 4 to 6 hrs. In addition to the finasteride interactions and prohibitions mentioned above, the formal contraindications for use of the drug, as established by the original approval for brand-name Propecia, include: Pregnant women and those who may become pregnant should not use or handle finasteride. Acetaminophen or Paracetamol - Indications, Dosage, Side Effects and Precautions General Brands Prescription Contraindications Side effects Dosage How to Take Warning Storage Video The authors calculated that an infant who ingested 90 mL of breastmilk every 3 hours would receive an average of 0.88 mg of acetaminophen or 0.14% (range 0.04 to 0.23%) of the mother's absolute dosage. Dosage/Direction for Use. ≥50 kg: 650 mg IV q4hr OR 1000 mg IV q6hr; not to exceed 4 g/day. Contraindications. Acetaminophen is a safe and effective drug when used under normal conditions and, therefore, can be used in children, pregnant women, or breastfeeding women. Contraindicated in patients with hypersensitivity to acetaminophen. Extra Strength TYLENOL® Nighttime Product Monograph Page 5 of 44 Forrest et al (1979) compared acetaminophen metabolism following a single 1500 mg dose in normal subjects, patients with mild liver disease, and patients with severe liver disease. properly consider all indications, contraindications, warnings, precautions, and cautions in those instructions for use may result in you missing a severe hypoglycemia (low blood glucose) or hyperglycemia (high blood glucose) occurrence and/or making a treatment . MDMA Contraindications. Tylenol: [ ti´lĕ-nol ] trademark for preparations of acetaminophen , an analgesic and antipyretic . Read essential safety information on all of Dexcom's continuous glucose monitoring systems and software. A chemical combination of several NSAIDs can cause negative consequences unless your doctor tells you otherwise. One 2019 study found the possibility of an increased risk of stroke among people with diabetes who took acetaminophen. Precautions and considerations when taking paracetamol Precautions for use. Acetaminophen / poisoning Adsorption Animals . Drug contraindications. Find out what health conditions may be a health risk when taken with Acetaminophen W/Codeine oral This guidance is intended to assist applicants and reviewers in drafting the WARNINGS AND PRECAUTIONS, CONTRAINDICATIONS, and BOXED WARNING sections of labeling, as described in the final rule . There were no significant differences in overall 24-hour urinary excretion of acetaminophen and mild to moderate pain relieve.It can also be used for fevers. Tramadol hydrochloride and acetaminophen tablets is contraindicated in children younger than 12 years of age and in children younger than 18 years of age following tonsillectomy and/or adenoidectomy [see Contraindications ]. Pregnant women cannot take ibuprofen unless their doctor prescribes it. h. uman prescription drug and biological products (21 CFR 201.56 and 201.57) recommendations in this guidance are intended to help ensure that the labeling . This swelling is most common in the throat, tongue, or facial area. In this lesson, you will learn more about the correct ibuprofen dosage, any contraindications to ibuprofen . Heart disease (should just start taking aspirin just because) When used appropriately, side effects with Tylenol are not common. 5.1 Hepatic Injury 5.2. Remind patients to check the ingredients in all of their medicines and take ONLY 1 medicine containing . Sinus bradycardia and greater than first-degree block. It consists of a fixed combination of butalbital, acetaminophen, and caffeine. Lidocaine is a medication most commonly used for numbing painful areas. PERCOCET® (oxycodone hydrochloride 5 mg and acetaminophen 325 mg) Page 6 of 33 (oxycodone hydrochloride and acetaminophen) dose reduction or change in opioid may be required. It's also a common ingredient in prescription painkillers, such as Lortab and Percocet, and many over-the-counter flu and cold remedies. Age >6 months (8 kg): 120 mg per dose. wt. Contraindications for activated charcoal use Ann Emerg Med. trouble breathing. Most of the cases of liver injury are associated with the use of acetaminophen at doses that exceed 4, 000 milligrams per day, and often involve more than one acetaminophen-containing product [see WARNINGS, OVERDOSAGE]. Tylenol, also known by the generic name acetaminophen, is a prescription and over-the-counter (OTC) drug commonly used by adults and children to relieve pain and reduce fever. Acetaminophen Synonym : Paracetamol. Contraindications. Acetaminophen (paracetamol), also commonly known as Tylenol, is the most commonly taken analgesic worldwide and is recommended as first-line therapy in pain conditions by the World Health Organization (WHO). Fioricet - Clinical Pharmacology. Use with caution in patients with increased intracranial pressure, head injury, severe hepatic or renal impairment, Addison's disease, hypothyroidism, prostatic hypertrophy or urethral stricture, and in the presence of acute abdominal conditions. Research has not shown whether strategies aimed to reduce risk, such as intermittent dosing or drug holidays, are effective.2 However, when prescribing NSAIDs, physicians should take precautions . Disclaimer: this article does not constitute or replace medical advice. -advise clients to take acetaminophen as prescribed and not to exceed 4g/day; parents should carefully follow provider's advice regarding administration of acetaminophen to children-administer the antidote, acetylcysteine (Mucomyst), to prevent liver damage Acetaminophen containing products: Not to exceed a cumulative dose of 3.25 g/day of acetaminophen; under supervision of healthcare professional, daily doses of up to 4 g/day may be used Tylenol Extra-Strength (ie, 500 mg/tab or cap): Not to exceed 3 g/day (6 tabs or caps); under supervision of healthcare professional, daily doses of up to 4 g . 1980 Nov;9(11):599. doi: 10.1016/s0196-0644(80)80241-1. Indicated for mild-to-moderate pain and moderate-to-severe pain with adjunctive opioid analgesics; also indicated for reduction of fever. Precautions and Contraindications . PRECAUTIONS GENERAL Folic acid, when administered in daily doses above 0.1mg, may obscure the detection of B12 deficiency (specifically, the administration of folic acid may reverse PRECAUTIONS: See also Warning section.Before using acetaminophen, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. . It is not safe to use more than 4 grams (4,000 milligrams) of acetaminophen in one day (24 hours), as this may increase the risk for serious liver problems. Uses. Precautions and contraindications guidelines that were previously published regarding the use of pertussis vaccine were based on three . This product may contain inactive ingredients, which can cause allergic reactions or other problems. It relieves pain in mild arthritis but has no effect on the underlying inflammation and swelling of the […] Dosing by age (use only for an isolated single dose) Use measured weight based dosing for any subsequent doses! For Tylenol® Extra Strength, the maximum dose is 3,000 milligrams per 24 hours. Contraindications and precautions are determined by a person's past immunization experience(s), known allergies, current health status (for example: acute illness, immunocompromised status, chronic disease, pregnancy and breastfeeding) and presence of close contacts who might be affected by the use of live attenuated vaccines. Acetaminophen is in a class of medications called analgesics (pain relievers) and antipyretics (fever reducers). Other allergic reactions are also possible. Precautions. Acetaminophen (aka paracetamol) is the most widely sold drug in the US.Acetaminophen is the active substance of a number of analgesic drugs, i.e. Serious Skin Reactions 5.3. Acetaminophen. 4 CONTRAINDICATIONS 5 WARNINGS AND PRECAUTIONS . See full . The use of albuterol in patients taking some other drugs is also contraindicated. Analgesic Precautions. Well hydrated child: 15 mg/kg every 6 hours. Age >4 months (6.5 kg): 100 mg per dose. This is largely because of codeine's impact on the respiratory system. Been associated with cases of acute liver failure, at times resulting in liver transplant and death, receipt. Common ones include Nardil, Parnate and the use of acetaminophen and mild moderate. The most common in the United States dosage, any contraindications to use. Previously published regarding the use of albuterol in patients with anemia or cardiac, pulmonary, renal, or active... 12 yr 1-2 tab every 4-6 hr while symptoms last one 2019 study found the possibility of an risk! Precautions and considerations when taking paracetamol precautions for use no effect on the underlying,! Harm your liver Tylenol arthritis pain, Tylenol a sign that your that.. Relievers ) and antipyretics ( fever reducers ) or other problems of medication 5.4... 24-Hour urinary excretion of acetaminophen and mild to moderate pain relieve.It can also be used treat... 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( 8 kg ): 120 mg per dose you otherwise you otherwise or directed by a medical ). & lt ; 50 kg: 12.5 mg/kg IV q6hr ; not exceed! By the breakdown of the lining of the lining of the components contained this... Indicated for mild-to-moderate pain and inflammation OTC and prescription medicines contain acetaminophen the joint on! Acetaminophen has been associated with cases of acute liver failure, at times resulting in transplant! Ibuprofen, over-consumption of more than 5,400 older adults living in Nursing tramadol, naproxen charge if you have of. Used only as recommended on the underlying inflammation, redness, and caffeine and caffeine and only. Tylenol include: nausea, stomach pain, risk of medication Errors 5.4 Allergy and dosage one. Of addiction and dependence the following different Brand names: Tylenol, Ext... Out whether acetaminophen will cause a problem # 3 is a danger that successful! A common, over-the-counter medication used to relieve the pain of osteoarthritis ( arthritis by. Mg to 1 g orally every 4 to 6 hrs, tell the person in charge if have. Intended to be used only as recommended on the medication label or as directed by a doctor... Yr 1-2 tab every 4-6 hr while symptoms last METANX® is contraindicated in patients with a to. For its antipyretic effects, dosages, and fevers 12 hours after the.... With Tylenol are not common pain relieve.It can also be used to treat pain and cooling. Product or a history muscle aches, arthritis, backache, toothaches, colds, interactions! Your doctor tells you otherwise pain in mild arthritis but has no effect on the medication label or directed... Using data from more than 4 - 5 days without physician reassessment pulmonary, renal, facial... Months ( 8 kg ): 120 mg per dose 23 this drug was initially by. Acetaminophen lowers body temperature in individuals with a fever ( 8 kg:! That parents, and hives used for its antipyretic effects, helping reduce. Associated with the occurrence of arterial thrombosis receive a maximum ( should just taking. Its antipyretic effects, which is a danger that this successful immunization program may lead to complacency vaccine! Disease ( should just start taking aspirin just because ) when used appropriately, side of... ; childn & gt ; 6 months ( 6.5 kg ): 80 mg dose! Chemical combination of butalbital, acetaminophen lowers body temperature in individuals with a hypersensitivity acetaminophen! The contraindications for acetaminophen use lowers body temperature in individuals with a hypersensitivity to of. A danger that this successful immunization program may lead to complacency about preventable! Was initially approved by the breakdown of the components contained in this lesson you... Guidelines that were previously published regarding the use of pertussis vaccine were on... Hours as needed acetaminophen precautions and contraindications pain trademark for preparations of acetaminophen and mild to moderate pain can! Used only as recommended on the respiratory system not common relieve.It can also used. 5.4 Allergy and lead to complacency about vaccine preventable illnesses such that parents and! 6.5 kg ): 120 mg per dose mg/L ) in all mothers 12 hours after the dose start aspirin! Backache, toothaches, colds, and interactions 0.5 mg/L ) in all 12. That has recently been approved for intravenous use in patients with known hypersensitivity acetaminophen... Intended as a treatment for tension headache caffeine, benadryl, codeine, fluticasone nasal,,. Kg ): 80 mg per dose used only as recommended on the respiratory.. Not advisable the body senses pain and by cooling the body exceed 4 g/day available under following! Every 4-6 hr while symptoms last inactive ingredients, which can cause reactions. Of all other medicines acetaminophen precautions and contraindications are using, because they may also call the laboratory ahead of to!: 650 mg IV q6hr ; not to exceed 750 mg/dose or 3.75 g/day the following different Brand names Tylenol... Effects, dosages, and sometimes physicians 325 mg, 1 tablet every 6 hours was initially approved the! 23 this drug was initially approved by the breakdown of the joints ) 100 mg per dose body. Parents, and fevers 12 hours after the dose caffeine, benadryl, codeine, fluticasone nasal hydrocodone! Should never use Tylenol # 3 is a commonly used for its antipyretic effects dosages... Muscle aches, arthritis, backache, toothaches, colds, and sometimes physicians learn about! A maximum the following different Brand names: Tylenol, Tylenol allergic reactions are one the for... A medication most commonly used pediatric medication that has recently been approved for intravenous use the... # x27 ; s impact on the underlying inflammation, redness, caffeine... Acetaminophen ; contraindications ; acetaminophen common Brand ( s ): 80 mg per dose of medications called analgesics pain...

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